Now that you say that I could see a situation similar to Woodrow Wilson's wife happen if Reagan doesn't fully recover from the assassination attempt. Obviously the Vice president doesn't have as many duties as the President but I could 100% see a scenario where Nancy, in her role as Second Life, keeps her husband out of the spotlight or even make the decision for example how Reagan should vote on a tiebreaker.I mean, there's also the possibility that he were to resign: he absolutely depended on Nancy to keep him on a steady tiller. For all of Reagan's hard-edged conservatism, he was a romantic at heart. It's part of why he got on with Margaret Thatcher so well. It's hard to imagine, but she too had this sort of romantic view of things, definitely with Denis Thatcher, but also used those aspects of her elsewhere; hence Mitterand's famous quote, "She's got the eyes of Caligula and the mouth of Marilyn Monroe."