Just to name a few that come to mind...
1. A more outward looking Egypt, one that concerns itself with empire building not just in the Levant, but also Cyprus, Cilicia, Pamphylia, maybe even Greece and Libya, Tunisia, Algeria as well.
2. Alternate silks. The Europeans were making their own wild silks during Classical Antiquity... maybe this goes somewhere? Alternatively, I saw
@Revachah I believe positing a West African kind of silk a few months back.
3. Moose Domestication in North America or Siberia.
4. A successful Franco-Mongol Alliance that is able to crush the Mamluks. What happens to Islam in the long term? Is it replaced with something more akin to the Baha'i Faith? Perhaps it disintegrates and becomes an ethnic religion practiced only by Arabs.
5. No Massacre of the Latins, which likely butterflies the 4th Crusade.
6. Cancelling the Gregorian Reforms. Simony remains the norm and priests are permitted to marry and have children in the Catholic Church. Perhaps the schism between Eastern Orthodoxy and Catholicism can be healed sooner?
7. Jesus becoming enveloped in Zealotry.
8. Jesus marrying and fathering children, perhaps fostering a different religious movement that can be syncretized more with some kind of Greco-Roman religion.
9. Siddhartha Gautama actually dies while he is starving himself during his bout with asceticism, resulting in an abortion of Buddhism.
10. Emperor Trajan bans the practice of Judaism and forces all Jews within his empire to assimilate following the little-discussed Kitos War. Do Christians hurry to differentiate themselves from Jews and syncretize their religion more with Greco-Roman polytheism and/or Neoplatonism, or are they too forced to give up their faith?