August 1507: Anne of York, Duchess of Burgundy, dies in childbirth on the 8th of August, giving him a third son, named Eduard, who died shortly after birth. The next was the death of his 2 other sons of typhoid fever. With this, Philip would realize that he needed a male heir.
September 1507: Leonor of Aragon gives birth to a daughter, named Isabella after her Castilian grandmother. Edward, Duke of Monmouth, falls ill and dies, as he was always sickly.
January 1508: Margery Wentworth gives birth to a daughter, Jane Fitzroy. It is discovered that Edward Fitzroy, Earl of Cambridge has eloped with Margery, which scandalizes the court. The younger Edward is the probable father, but Margery cannot be sure.
March 1508: Philip, Duke of Burgundy married for the second time to Mary of Scotland. The couple meet and the ceremony is done with much pomp. However, Philip wastes no time and announces to his court he expects a new heir by the next year.
April 1508: The King of England undergoes a health scare and thus pressure is increased on the Prince and Princess of Wales to deliver a healthy child. Margaret had miscarried her last child in August, meanwhile Queen Anne gave birth to a daughter, Eleanor in December. Finally, after waiting several months to secure the pregnancy, Margaret, Princess of Wales announces a pregnancy. Elated at this news, the King stages a full recovery for the time being and the Queen and Princess of Wales form a friendly, close, bond.
June 1508: Queen Marie of France gives birth to a healthy son, Charles, Dauphin of France. Marie recovers well. The young girl seems to be nervous as Queen but her husband is equally young and inexperienced and she becomes a true decoration to the court, as she is notably beautiful.
July 1508: On the 11th of June, Margaret of France, Princess of Wales gives birth to the Prince William of Wales, second heir to the English throne. She recovers well and the Prince seems very healthy. With an heir to the throne Edward V seems at peace and within a week of his grandson's birth he died, shortly followed by his ex-mistress, Margaret Wentworth, Countess of Cambridge, after she suffers a miscarriage. And thus, within a week the Prince and Princess of Wales had brought a new royal family to the front of English politics.