For the Seleucids, Harsiesi’s revolt against the Ptolemies in 131 BC is successful, dethroning the Ptolemies, in the midst of a civil war between Ptolemy VIII Physkon and Cleopatra II. Cleopatra II petitions the Seleucid ruler Antiochus VII Sidetes to crush the native revolt and restore her on the throne, in return for becoming a vassal and assisting him in his campaigns. The Seleucids defeat both the divided native Egyptian rebellion and Ptolemy VIII, who is forced into exile in Cyrene, dying mysteriously shortly after. With additional Egyptian support, Antiochus VIII avoids the disastrous moves in Media and the ambush in Ecbatana, killing the Parthian king Phraates II instead. While the Parthians will try to release Antiochus’ brother Demetrius II and start a civil war, after this victory Antiochus should be able to defeat Demetrius and possibly affect a moderate Seleucid resurgence. Rome may be a problem, but it will be in Rome‘s interests not to have a powerful Parthian empire on it‘s eastern frontier, and may tolerate Seleucid moves.
For the Neo-Inca, that would be easy if you count Manco Incas’ revolt in 1536 as Neo-Inca. Just have the fire near the buildings where the Spanish took refuge not get put out and force the Spaniards out into the open, where they get overwhelmed one by one. Another is to have Manco Inca not order his general Quito to directly assault Lima instead of using the tactics that had worked well against the Spaniards and their cavalry thus far. Another is to have Hernando Pizzaro get killed at Ollantaytambo by a stray arrow to his face. Another is to have Paullu Inca side with Manco instead of the Spaniards. Another is to avoid Manco Inca’s assasssination by pro-Almagro supporters. There are countless scenarios.
