I agree that taking away Thomas Midgley might take leaded gasoline out of the picture. It is not intuitively obvious to put a heavy metal into liquid fuel, let alone a toxic one like lead. The American fuel industry would simply have to get along without it. As mentioned, Germany and Japan did not have it. The unleaded fuel era simply becomes industry standard as effort goes into earlier fuel injection, along with blending of aromatic hydrocarbons and ethanol. Aviation fuel in WWII without lead? Gasoline was rationed and refineries were controlled. Petroleum engineers would figure it out. In the strategy of fuel technology, lead was more of a short cut than a game changer.
What about refrigeration without Midgley? Too many researchers would be looking for better refrigerants and it would only be a matter of time before halogenated hydrocarbons would come along. In OTL, Frigidaire and DuPont were first in line. In the meantime, what was Dow Chemical doing? Union Carbide, American Cyanamid, Norsk Hydro, Rhone-Poulenc, Bayer, BASF?
If the Germans made the discovery, it would be “liberated” after World War II. BASF invented tape recording in the thirties but never exported it. Americans brought the machines back after the war, reverse engineered them, and revolutionized entertainment technology.