Well...
According to The Big Book of Thugs, Devil Ance Hatfield died in 1921 so he
does have a chance to set it off again before he dies.
BUT!
The book also notes that by then, the families had actually intermarried
"to an unusual degree". (I'd say "cue jokes about Appalachian spouse-choosing traditions", except it is implied that in this case it isn't one.)