In 1868, Mary Gladstone, who achieved notability as advisor, confidante and private secretary, to her father, William Ewart Gladstone, who had succeeded as Prime Minister in this year.
On March 1st, 1880, at the age of 41, Richard Grosvenor, 1st Baron Stalbridge, as the incumbent member of parliament for the constituency of Flintshire, with only 30 days until the general election, William E. Gladstone, was in a panic of who to pick.
This is where Mary came into her own, she had attained a fair degree of political influence by controlling access to him, and was able to persuade her father, to allow her to sit in the election.
At the age of 33 years old, Mary becomes the first female elected to sit in Parliament, elected in the same year as her brother, Herbert Gladstone, 1st Viscount Gladstone, meaning that William E. Gladstone, had three of his children in Parliament, the other child was William Henry Gladstone who was MP for East Worcestershire.
Mary is given the title "minister without portfolio" and the duties of supporting her father during his Second ministry, from 1880-1885. In his Fourth ministry, Mary is made home secretary from .
On 19 May 1898, after the death of her father and then William Vernon Harcourt, stepping down as Liberal Leader in 8 December. On 6 February 1899, Mary was able to beat Campbell-Bannerman and succeeded Sir William Vernon Harcourt as Leader of the Liberals in the House of Commons and in 1906 became the first female Prime Minister.