1518: Henry Tudor, Prince of Wales is born.
1530: Mary Tudor marries Francis III of Brittany, the Dauphin of France.
1534: The 16 year old Henry Tudor, Prince of Wales, dies of an unknown illness.
1535: Mary Tudor becomes pregnant for the first time and gives birth to Catherine de Valois.
1536: Catherine of Aragon dies at the age of 50. Soon after, her daughter is made a widow as the Duke of Brittany dies of a mysterious illness. This causes her to suffer a miscarriage of her second child, which the midwives said would have been a son and heir. Her daughter, Catherine de Valois, is now Catherine I of Brittany. Henry Fitzroy, Duke of Richmond and Somerset dies, unmarried.
1537: Henry VIII of England marries the Infanta Maria of Portugal.
1539: Henry VIII of England and Maria of Portugal welcome their first child, Edward Tudor, Prince of Wales.
1540: Henry VIII of England welcomes a second son, named Edmund Tudor and he is created the Duke of York.
1541: Mary Tudor accepts independently, the proposal of Luis, Duke of Beja in Portugal. She travels without her daughter to meet with her new husband and would enjoy her third child, giving birth to a son named Duarte of Beja.
1543: Maria of Portugal becomes pregnant for a third and final time, giving birth to a third, short-lived son named Henry Tudor, who before his death in December, is made the Duke of Clarence.
1546: Mary Tudor gives birth for a final time, this time with a daughter, named Isabella Magdalena of Beja.
1547: Henry VIII dies at the age of 55, leaving a widow with 2 sons.
1550: Mary Tudor dies at the age of 34.
Henry VIII of England (b.1491: d.1547) m. Catherine of Aragon (b.1485: d.1536) (a), Maria of Portugal (b.1521: d.1555) (b)
1a) Stillborn Girl (c.1510)
2a) Henry Tudor, Prince of Wales (b.1511: d.1511)
3a) Henry Tudor, Prince of Wales (b.1513: d.1513)
4a) Henry Tudor, Prince of Wales (b.1515: d.1515)
5a) Mary Tudor (b.1516) m. Francis III of Brittany, Dauphin of France (b.1518: d.1536) (a), Luis of Portugal, Duke of Beja (b.1506: d.1555) (b)
1a) Catherine de Valois, I of Brittany (b.1534)
2a) Miscarriage (c.1536)
3a) Duarte of Beja (b.1541)
4a) Isabella Magdalena of Beja (b.1546)
6a) Henry Tudor, Prince of Wales (b.1518: d.1514)
7b) Edward VI of England (b.1539) m. Elisabeth de Valois (b.1545)
1a) Miscarriage (c.1562)
2a) Mary Tudor (b.1564)
3a) Elizabeth Tudor (b.1566)
4a) Edward Tudor, Prince of Wales (b.1570)
8b) Edmund Tudor, Duke of York (b.1540) m. Renata of Lorraine (b.1544) (a)
1a) Thomas of York (b.1569: d.1570)
2a) Eleanor of York (b.1572)
3a) Margaret of York (b.1574)
4a) Henry of York (b.1575)
5a) Catherine of York (b.1576)
7a) Stillborn Girl (c.1580)
8a) Edward of York (b.1581)
9b) Henry Tudor, Duke of Clarence (b.1543: d.1543)