That's a pile of mountains that just got turned to beachfront property!
The effect of that shift is going to be prehistoric; don't forget things like the Second Punic war had Hannibal marching from Spain through France and into Italy. I'd go so far as to say that this butterflies things from the era of the Roman Republic.
There are going to be cities on the Biscay Channel that don't exist in OTL; there are going to be rivers draining into it that didn't in OTL. The PoD is going to be so early (Prehistoric) that mass migrations of human tribes in the Roman era and later are going to be messed up. Iberia might become mostly North African culturally; it might not even be a part of Europe; alternatively, the Biscay Channel might be an important trading route that could allow English Wool easy access into Italy and Greece.
There isn't going to be WW2 as we know it, because in all likelihood there is no France and Germany as we know them at this point...