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Would it have ever been plausible at any time in american history whereby a large spread systematic extermination program similar to what the nazis employed primarily against the jews in the holocaust, ever been applied to its african american populace?

Perhaps less likely at the national level but in any of the individual states even? Assuming following the end of slavery there became the belief in a need for a "final solution" for its black population?

Can anyone think of any changes in history that could have resulted in this? Maybe a rise of fascism/eugenics movement? Or is this really ASB?
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