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Louis VI the Roman, son of Louis IV of Bavaria, married a daughter of Casimir III Great of Poland, Kunigunde in 1345. They had no surviving children. But what if they had following children (say Louis is ITTL obsessed with his wife's beauty and doesn't care about money and doesn't return to Bavaria without his wife):
Vladislaus (1345-1390)
Louis the Younger (1347-1395)
stillborn son (1348)
Margaret (1352-1400)
The birth of Louis's sons block Otto V the Lazy the road to the Brandenburgian throne (so no Brandenburg for Luxembourgs) and could mean (not sure about it, but if Vladislaus is not retarded like Casimir of Słupsk and is Elector) no Poland for Louis of Anjou (less likely)/Jogaila (more likely) @Jan Olbracht