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At the age of 18 Prince Juan of Asturias son of Ferdinand of Aragon and Isabella of Castille married Archduchess Margaret of Austria in April, 1497. Six months later, on the way to the wedding of his older sister in Portugal, he died in Salamanca possibly from tuberculosis. His wife was left pregnant and later gave birth to a stillborn child. Juan's death, followed closely by those of his elder sister (Isabel, Queen-consort of Portugal) and her only child (Miguel) led to the inheritance of the Spanish kingdoms by the Habsburgs, descendants of his younger sister Juana, who had married the Archduchess Margaret's brother Philip the Handsome.
WI Juan's posthumus child had lived? How is this altering History? Any thoughts?