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On the day Ali ibn Talib, the son-in-law of Muhammad and later inspiration for Shi'a Islam, was assassinated by a Kharijite zealot with a poisoned sword similar attempts were made on Mu'awiyya and Amr al-As, the founder of the Umayyad Dynasty and the Muslim governor of Egypt respectively, that both failed.

What if the Kharijites got all three of their intended targets? What impact would this have on the development of Islam for all three of the heavyweights of the Muslim world and top contenders for the caliphate following Uthman's death to go down in the same day?
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