Essentially the Battle of Lepanto is still victorious, but the plan to seize the Dardanelles succeeds this time and eventually leads to a rump Ottamon Empire.
The Balkan kingdoms quickly try to gobble as much as possible(Serbia, Wallachia, Austria, and Venice) which ends with Austria gaining back most of Hungary, Venice getting almost all the coast and western Turkey. Wallachia spreads out to take some coast and tries to go north but is turned back by the Crimeans. Serbia takes whatever others have yet to take.
In Italy Venice is too focused on securing the east Mediterranean to do much more than secure its aims. Genoa and Milan realize that when the Venetians finish they will turn on northern Italy. So to combat this they form an Italian Republic compromised of the Milanese, Genoese, Parmese, etc. The Papal States remains much the same except for demanding some land from Spanish Naples which is granted.
Poland has a Vasa come to throne after defeating Austrian forces attempting to put Maximillian on the throne. Russia meagerly attempted to put up a candidate and thus gave a casus belli to the new Polish-Swedish Union.
In Africa the fall of the OE makes certain the Moroccon and Algerian forces become stronger. Morocco quickly takes over the Portugese cities and fights off a Spanish attempt to retake them, albeit the attempt was merely to show Portugal Spain was an ally. The Spanish focused more on Algeria and took a sizable area. Now the Knights, gathering support from the still functional Catholic League attacks the Tunisian cost and sets up a new Catholic Kingdom. Fearing persecution many muslims flee into Algeria. There the Algerian beydom declares itself separate from the Ottoman Empire and turns back the Knights and Spanish, but just barely, leaving all sides too exhausted to fight anymore, leaving Morocco free to continue to expand southwards. The Egyptians also rebel from the Ottomans and take most of North Africa all the way too Tunis. But when the Catholic League supported Knights attacked they had to retreat until the Knights turned their attention to Algeria. The Egyptians also seize the Holy Land when the Persians renew an attack on the Ottomans, as well as a new Venetian attack leaving the Ottomans severely crippled.
Russia on the other hand has no such stability and is a constant battleground. As the Polish-Swedish Union turns back the Austrian armies they focus on Russia which had recently been incredibly weakend. A fearful Crimea realizing that without making itself a strong opponent was going to be gobbled by one of the surrounding powers, made a much stronger push than historically against Russia. With the burning of Moscow and the destruction of Russia's armies the Crimeans quickly return home due to Wallachian aggression. Sweden and Poland quickly strike against the unprepared Russians leading to a complete collapse into anarchy and civil war. But all is not well as Sweden and Poland soon start squabling over the remains with Sweden gaining the upperhand and seizing the Baltic territory of Poland for the most part.
In Northern Europe the protestant states become much stronger. Brandenburg, Saxony, and most of the Hanseatic League unite due to Austrian aggression. When the Danes attempt to weaken this new German Empire thinking them a dis-united weak empire they are turned back and lose much of their german possesions. Sweden capitalizing on this seizes Norway during a revolt by Norweigan lords. Denmark is left a rump state with many lords and few territories.
In the UK a couple things changed. The Yorkist Revolts for Catholicism were much stronger and thus meeting a much harsher reprisal. Then with Spain having quashed the Dutch revolt due to not having to be in the Mediterranean all that much they launch a much stronger Spanish Armada. It still hits the storms but is able to continue, albeit much weaker. They land at the north near York and the Peasant sentiment is very much against the crown. Following that a combined Scot-York-Spanish coalition march on London. They are just barely turned back which leads to the combined kingdom of Scotland-Norfolk to appear. Ireland, seizing the oppurtunity, rebels and creates itself as a new unified kingdom. England is left with Wales and England south of York for the most part.
The Middle East now has a Safavid caliphate as the dominant force. Throwing back the Ottomans from Baghdad, Aleppo, and Armenia they weaken the Turks even more. Because of the fall of the Ottomans, Qasim the Great of Yemen quickly rebels and, having no real competition, seizes most of the holy land in Arabia, including Mecca but does not wish to earn the enimity of the Egyptians so instead turns east, letting Medina and other cities become city-states or under the rule of small chiefdoms. Oman attempts to also make its mark and take land to the north but has its supply lines cut by the local tribes who ally to fight off the Omani aggression. Eventually the Safavids come south and throws the Omani back. Because of these string of defeats both Yemen and Portugal attack Oman. Yemen moves to the east and Portugal takes the rest. Yemen, seeking to digest its new territories sits on the border and lets Portugal take the furthest east of Oman. Portugal, now much too involved in its colonies does the same. At this same time the Ottomans focus on crushing any revolts that occurs and lets other nations take bits off their lands retreating to a much smaller demense.