WI Seleucus I Nicator isn't assassinated in 281 BCE?

When they didn't have problems in the west, specifically with the Romans, they were more than capable of stabalizing things in the east.

And what's preventing them from having problems from the Romans. Nothing about Seleucus I's assassination means that Rome won't be a power to contend with the Seleucids at some point.
 
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