The Seleucids arguably reached their lowest point pre-Magnesia in this time period, with political instability, rebellions, and constant warfare in Syria wracking the Seleucid state. Antiochus III was one of the more energetic Seleucid rulers, and he managed to get rid of the influence of powerful courtiers, supress rebellions throughout the empire, and despite a defeat at Raphia in 217 BC, managed to revitalize the Seleucids, enough to penetrate Egypt itself in his wars with the Ptolemies and intervene in Greece, something which would not be considered just a few decades prior. While another could've replicated the same general grand strategy and done the same, it was also possible for the empire to continue to decline. Say that everything goes wrong for the Seleucids and right for their enemies, that Antiochus III never comes to the throne. We have Molon ruling in Media, Alexander ruling in Persis, a completely independent Greco-Bactrian kingdom, an Achaeid kingdom, possibly Ptolemaic Damascus and even Antioch, and all the "lesser diadochi" take their pieces, such as Armenia, Pontus, Pergamon, and others, leaving us with a core in Mesopotamia and parts of Syria. What would happen from this point onward? Would the Seleucids be able to survive in a reduced form in their core of Mesopotamia and parts of Syria? Would Rome rise earlier and simply make protectorates out of all of them? Or could the various Anatolian kingdoms have a better chance, like what Pontus managed to pull of IOTL?