WI Peter II of Russia doesn't get smallpox?

As says the title: Peter II of Russia, the grandson of Peter I, doesn't get smallpox and so doesn't die as a 14 years old in 1730, but instead he lives at least as long as his grandfather. How could his reign look like? And what would happen to Anna and Elizabeth?
 
Pyotr II was chosen to succeed his stepgrandmother Ekaterina I because the "new" nobility of Russia had their own interests at heart, and were disinclined to prop the elder daughters of both Peter the Great and his brother Ivan V (Anna Petrovna and Ekaterina Ivanovna) onto the throne more because of fear that their husbands (the duke of Holstein, and the abusive duke of Mecklenburg-Schwerin) would use Russian politics to their own advantage.
If he were to become Emperor, he might take one of two courses.
1) He might rule much the same as what Peter the Great and Catherine the Great did - autocratically (there is a story involving him and Aleksandr Danilovich Menshikov and a gift Pyotr had given to his sister Natalia to support this theory) and opening Russia up still more to Western ideas and influences.
Or 2) He might tread the same path as his cousins Pyotr III and Pavel I. Reactionary measures against the preceding reign (Pyotr reversed Russian foreign policies on his accession, thereby forfeiting all the gains that Empress Yelizaveta had made, an act remembered in Germany as the Miracle of the House of Brandenburg. And Paul, well, he had some odd ideas like invading India across Asia and believing his mother used to grind up glass in his food).
Or, there is always the possibility of a third option that the government in St. Petersburg would be a petticoat government, since he was reportedly very close to his sister Natalia (d. 1728), his aunt (and future Empress) Yelizaveta, and he was originally slated to marry Menshikov's daughter, Maria Alexandrovna Menshikova - which means that Prince Menshikov would've had a say in Russian affairs through his daughter, ergo, rule by women.
If he were to live, another bride proposed for him was (oddly enough) apparently the Infanta Mariana Vittoria of Spain (slighted fiancee of Louis XV and later Queen of Portugal). But given she would be Catholic and unlikely to convert - a Protestant princess from Germany would be more acceptalble.
One could marry him off to the Princess Elisabeth of Mecklenburg-Schwerin (OTL Anna Leopoldovna, b. 1718), the daughter of the aforementioned Ekaterina Ivanovna - thereby uniting the Petrovich and Ivanovich claims).
 
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