What if Frank Herbert, sometime before 1962, lost interest in putting together his "desert novel" and never shopped it around? Or if Campbell had never started publishing his "Dune Stories" in Analog magazine? Or if Chilton Books never made the risk of publishing the novel itself?

How is Science Fiction and Fantasy affected, both in the nearish term (late 1960's to 1970's) and from there? How does this change to the genres, in turn, affect pop culture at large (aside from the pointlessly obvious lack of Lynch's adaptation)? And are there larger effects still that emanate from there?

(Last time discussed) (inspiration for the thread)
Space sci-fi had a bit of a dormant period between 1970 and 1977, as the real moon landings were tough acts to follow. When Star Wars broke out in 1977, the space adventure genre was dominated with action, battle, robots, computers, etc., and Dune was a different series of stories. I might think science fiction an fantasy would be affected little, as Lord of the Rings and Star Trek would still be there. Babylon 5, Battlestar Galactic and others pretty much follow the course of computers and special effects.