I was thinking that if the Black Death plague would have had a death ratio of 80-90% of people in Europe/Middle East just like smallpox had in many areas of America when Europeans brought it there, probably the European civilizations could have not recover of it.
In that case, would some Asian civilization took over of such huge amount of territories (virtually depopulated) and resettled it? Or maybe it was too challenging for any of them?
Or maybe some of the European civilizations could have rebound in some decades and took over of most of the continent?