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In otl many consider Mithradates as the second Hannibal. He came to power after overthrowing his mother and started the great Mithradic wars. He defeated the Romans and conquered Asia, as well as getting most of Greece form an alliance under his banner to oppose the Romans. In OTL he was defeated in Greece by Sulla and 5 legions, but always escaped. He also escaped om Pompeii and dealt many defeats to the Romans. SO WI he and the Grecian alliance successfully defeat the Romans. How would events in the ancient world play out.
For those who don't know him here is some links: http://www.britannica.com/EBchecked/topic/386057/Mithradates-VI-Eupator http://en.wikipedia.org/wiki/Mithridates_VI_of_Pontus
So what happens to the history of antiquity.