Ok, so I've been thinking about this a bit and here's some possible consequences of Maria Theresa losing the War of Austrian Succession.
First I'm assuming a POD involving the Battle of Dettingen
While Charles VII of the HRE will be hoping to get all of the "Habsburg Inheritance" he will quickly run into a united opposition from his allies, primarily France and Prussia. Now while France had plans to divide up the Habsburg lands between themselves, Prussia, Saxony, and Bavaria, those exact plans probably NOT be put into place.
But basically the Habsburg lands in the German portions of the HRE would be taken up by Bavaria, Saxony, and Prussia. Charles VII would also be confirmed to be the King of Bohemia as well as the HRE Emperor.
The Habsburg holdings in Italy and the Austrian Netherlands, however could be tricky. While France has had designed on both lands for centuries, I'm not so sure the powers of Europe would tolerate Louis XV keeping that much territory.
I could see Louis deciding to keep the Italian duchies of Milan and Tuscany in exchange for turning the Austrian Netherlands into it's own statelet with someone of his choosing becoming the 'Duke of Belgium and Luxembourg'. Louis XV only had one son at this time, but several daughters so he could select a candidate, have that man marry one of his daughters, and exert tremendous influence over Belgium and Luxembourg.
During this, while Charles VII would push to force Maria Theresa off the Hungarian throne, this is where the forces of Europe would tell him no. There isn't a non-Habsburg alternative to her, so she'd get to keep it as a consolation prize.
However considering Charles VII's health I doubt he'd get to enjoy his new status for long, he'll probably die roughly when he did in RL, so his peacetime reign will have to be dominated by securing the succession for his heir, Maximillian Joseph, who ironically would reign as Emperor Maximillian III (his Bavarian numerals line up), however he and his uncles had no children, so the death of Maximillian III would open up the succession for the HRE throne once more.
Meanwhile, Maria Theresa would be sitting pretty in Hungary, breeding a huge brood of children like she did in RL, no doubt having gotten involved in the First Partition of Poland, with Prussia and Russia at her side on this one. And while this would let her expand her Hungarian Kingdom, and net her sons something of an inheritance... She'd be watching and waiting for her chance to try and once more claim the Habsburg lands.
So when Maximillian III dies, there'd be an even bigger War of Bavarian Succession, not just to Bavaria, but to everything that the Wittlesbach's took from Maria Theresa.
Now you might be asking how Maria Theresa could take on the powers of Europe when she failed the last time, well this time she's got her children and would have been making marriage alliances with them, giving her a bigger support base.
Not to mention that the alternative to Maria Theresa and her husband would probably be Prussia, which has grown by leaps and bounds and even in RL there were many who wanted to clip their wings a bit.
I could see a scenario emerging out of this in which Bohemia winds up outside of the hands of the HRE Emperor, i.e. the Bohemians either willingly chose a new monarch from a foreign dynasty, or they are 'convinced' to do this as part of creating a balance of power.