WI: Jorge de Lencastre is legitimized and becomes King of Portugal?

For many of us AH.com'ers who know the many WI's involving Miguel da Paz, knew that his rise to power came at the expense of the death of Isabel, Princess of Asturias' first husband, Afonso, Prince of Portugal. who died in a suspicious riding accident in 1491.

Joao II, who was king of Portugal at the time, now had an heir in the form of Manuel, then Duke of Beja. Joao had previously killed Manuel's brother, the Duke of Viseu, as well as his brother in law, the Duke of Braganza. Manuel only escaped death because Joao saw him as a "harmless fool." Quite ironic that said fool stood to (and in OTL, did) succeed him. This worried Joao as he thought (and as it turned out not to be the case) Manuel would decentralize Portugal just as his father did after the death of the Duke of Coimbra.

Joao sought to legitimize his illegitimate son, Jorge de Lencastre, so that he would inherit the throne. This would be countered by a counter-campaign led by Joao's wife, and Manuel's brother, Leonor, and supported by Manuel's Order of Christ. Ultimately, the plan failed (the request was denied by Pope Alexander VI, that sneaky Borgia.) And though Joao's will was mostly carried out, it was interpreted in such a way that Jorge could not make a significant threat to Manuel's royal authority, ultimately culminating in reducing the Lencastrian household into minor Nobility as the Dukes and later Counts of Aviero.

But going back to the question on hand, what if Joao managed to successfully legitimize Jorge de Lencastre, and thus with it, bring about the Lencastrian branch of the House of Aviz on the throne of Portugal. Would this change up the centralization policies initiated by his father? Would colonialization and exploration continue under this hypothetical King Jorge's reign?
 
But going back to the question on hand, what if Joao managed to successfully legitimize Jorge de Lencastre, and thus with it, bring about the Lencastrian branch of the House of Aviz on the throne of Portugal. Would this change up the centralization policies initiated by his father? Would colonialization and exploration continue under this hypothetical King Jorge's reign?

I think it would. Even though João was ultimately unable to legitimise Jorge and turn him into his heir, he did manage to leave him in a considerably stenghened position, by making him Duke of coimbra and commander of the militairy orders of Aviz and Santiago. During the reign of Manuel, Jorge led the "official oppoistion" to the Portuguese court, and was quite active in matters of colonial policy.

Contrarily to Manuel and his Order of Christ, which saw Portuguese discoveries mostly as a crusade to spread christianity throughout the world, Jorge's party was more pragmatic and wanted to focus on commerce rather than religion. So, if Jorge became king, colonial policy would be very different.

Also, centralization would continue, especially since Jorge would certainly be unpopular among the nobility, and the Jews would probably not be expelled (IOTL they were among Jorge's most loyal partisans).

That said, I'm not sure what kind of PoD would be necessary for the legitimization to be successful. The kings of Spain were vehemently agains it, as was most of the Portuguese nobility and clergy. It was basicalla king John versus the world.

In my TL, which I just started yesterday, I'm playing around this by having Jorge's elder brother Afonso survive and then put Jorge in a position of influence by giving him the same militairy orders as got IOTL, plus all of the Order of Christ's gold and assets and making him viceroy of India.
 
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