WI Hemophilia wasn't sex linked

Being a weoman and having hemophilia is a very bad idea for obvious reasons.

I don't think it works that way, though. Menstrual discharge consists mostly of the lining of the uterus that has broken down, it's not blood flowing from a severed vein so they don't keep bleeding in that situation, as far as I know.

And women can have hemophilia, it just less likely. Their two X chromosomes have to carry the recessive gene to have hemophilia, whereas men only need their one X chromosome to carry the gene.

Basically, if hemophilia was not on a sex-linked gene, men and women would be equally likely to express the gene. Also, men could be non-symptomatic carriers as well as women, since their other chromosome pairs could have 1 hemophilia gene and 1 normal gene which would be dominant and keep them from having the disease.

EDIT: Allow me to demonstrate.

IOTL, *X=X chromosome with Hemophilia Gene. X=Normal X Chromosome. Y=Y chromosome, of course.

*XX=Queen Victoria, has gene but does not have the disease. XY=Prince Albert. He does not have the gene.

Their spawn could include: XX, *XX (has the mutant gene, but her X chromosome from Albert has the normal gene so she will not express the disease), *XY (Male, will be the only one to express the disease), and XY

IATL, *21=21st Chromosome with Hemophilia Gene, 21=Normal 21 Chromosome.

*2121=Queen Vic, *2121=Prince Albert.

Now, any of their children could be hemophilia free, have hemophilia, or be a carrier, and as the gene is not carried on a sex chromosome, the disease can occur regardless of gender. In short, hemophilia becomes much, much harder to track across generations.

And if they have 212121, they'll have Down Syndrome but that's a different thing.
 
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This actually otl, technically. Haemophilia C is not sex linked, but is rather rarer than A or B. Women have heavy menstrual flows apparently, but it doesnt seem to be life threatening. Of course, from what i can see, its a bit milder than A or B....
 
This actually otl, technically. Haemophilia C is not sex linked, but is rather rarer than A or B. Women have heavy menstrual flows apparently, but it doesnt seem to be life threatening. Of course, from what i can see, its a bit milder than A or B....

I was talking about hemophilia B, the same disease Alexei Nikolaevich had.
 
How do they fare in childbirth?

Good question. According to hemophilia.org, C is a pretty mild form, and bleeding problems vary massively from one person to the next, and even from event to event in one person.

With modern tech, it seems to be manageable, and it looks like a woman might have few problems - if she were lucky.

Apparently its also called Rosenthal's Syndrome, and its almost restricted to Ashkenazic Jews.
 
To get back to the original question, if a woman had something as nasty as regular haemophilia, she'd die almost certainly in child birth, unless she was in a modern major hospital.

Mind you, it wasnt common for actual hemophiliacs, as opposed to carriers, to make it to puberty.
 
If we were talking about the most common types, the world would probably be pretty different. :p For starters, there's their periods. From what I understand, women who are carriers of hemophilia may have menorrhagia. This isn't necessarily fatal, although in extreme cases it (menorrhagia, not necessarily hemophilia-related) can lead to death. It can also lead to unpleasant symptoms, like anemia. In the olden days, this would probably have been even more problematic than it already is. You're not cutting open a vein, but all that blood does come from somewhere and if you have coagulation problems it's going to be heavier than average.

If they had extremely intense symptoms, they would definitely die in childbirth. This means that Queen Victoria and the Tsarina Alexandra would have died after their first pregnancy, so Prince Alexei would not even have existed. If you wrote a TL like this, after a while you would have a world with radically different heirs and marriages and such.
 
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