IOTL, Frederick Hohenstaufen of Sicily became Holy Roman Emperor in 1216 after his rival, Otto of Brunswick, lost all credibility at the Battle of Bouvines. But what if Frederick had died between, say, 1212 and 1214. Before leaving for Germany, he'd had his infant son, Henry, crowned King of Sicily under the regency of his mother, Constance of Aragon. Apart from having a different King of Sicily and subsequent HRE, what else might have been different without stupor mundi?