In 1519 one of the most contested elections for Holy Roman Emperor occurred, the two main contenders were Francis I of France and Charles I of Spain and Duke of Burgundy. They both offered big bribes but Charles had the deeper pockets and it was Charles who won.
But what if Charles had suffered some sort of health crisis that convinced the Electors that Francis was the better choice, making him Emperor Franz I of the Holy Roman Empire?
How would history have played out with a French King as the Holy Roman Emperor in this era?