Francesca of Naples was the first (or second, depending on where you read) daughter of Joanna I of Naples and her second husband, Louis of Taranto. She was born in 1351 and apparently betrothed to the heir to the Aragonese throne (in this case, the future John I of Aragon), but died in 1352 aged just 8 months. Following her death, Joanna would adopt Charles of Durazzo, who would ultimately betray, overthrow and execute her.
What if Princess Francesca had lived long enough to marry John of Aragon, or someone else? Would her mother's OTL have been avoided? I think such a marriage could have led to an earlier reunion of Naples and Sicily, since John of Aragon's mother was the daughter of King Peter II of Sicily and sister to Kings Louis I and Frederick III of Sicily.
Any thoughts?