This is spot on.
And, as the aptly named
@isabella says, the rejection was definitely from Edward's end.
As to the What If in the OP, I'll concentrate on England, as my Spanish knowledge of the period is pretty sketchy. So, no Wydville match for Edward means:
- No massive family for the king to dole gifts and titles out to.
- No massive family of suddenly eligible singletons essentially flooding the marriage market.
- One of the people locked out of said market was Warwick (or his daughters).
- The diabolical marriage of one of Elizabeth's brothers to the aged, thrice widowed and immensely rich Duchess of Norfolk is avoided. That hurt the Wydvilles and the king.
- A different queen may help produce an heir rather earlier, which means that there's more chance of them being an adult when daddy dearest shuffles off his mortal coil.
Moreover, one of the people locked out of the marriage market was Richard Neville, better known as Warwick the Kingmaker. If he can get one of his girlies hitched to a Herbert, or Buckingham, then the bunfight between Richard and Clarence might be much less than it was in OTL. Also, he's generally not forced out of the picture by all these in-laws looking for trinkets, land, titles and favours.
Might be huge changes. Might avoid the Readeption. Which, of course, may mean that Edward of Westminster, by all accounts a nasty little scrote, is still out there, waiting for a chance.