It would probably cause a mass exodus of protestants to England, Scotland, Scandinavia and Germany, whic include the loss of a lot of capital (since many protestants were rich merchants). I assume it would take the Netherlands a century or so to recover that loss (we saw something similar in Flanders and Brabant after the protestants fled those areas when the Spanish recaptured it). I think the countries the Dutch would flee too would profit from it significantly (just like with the Hugenots).
Without the Netherlands as a counterweight, I suspect the French would be easily get the Rhineborder after the collapse of Spain (which is unavoidable, I suspect). France would probably be able to dominate the continent, or at least western parts (basicly what is now France, the Benelux, Germany and Denmark) and would probably the strongest country in Europe.
Colonial wise, I think Portugal, England and France would take over the spot of the Dutch. Although none will be as succesful as the VOC was in its highdays.
Without the Netherlands several economic and financial changes would be made a lot later. You basicly needed a country like the Netherlands for it to happen.COuntries like France, England and Scandinavia simply weren't as free as the Dutch republic in that regard and in those countries it was still the nobility that ruled supreme instead of the wealthy middle class, like in the Netherlands.