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What if Charles II, Duke of Orleans never caught the plague in 1545 and died? Charles V, Holy Roman Emperor through the Treaty of Crepy forced Francis I to give him the Duchies of Angouleme, Chatellerault, Bourbon, and Orleans and for him to marry either Maria of Spain or her cousin Anna of Austria with the Low Countries or Franche Comte as Maria's dowry and Milan as Anna's dowry. Which one do you think he would choose and how would this affect Europe as whole?
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