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I guess the best chance is some kind of combination of diseases and pests preventing the crop growing well in that area
I wonder what would be the consequences.
The worst of the triangual trade, with the slave 'middle passage' would not emerge with the power that it did in otl.
Also with refined sugar delayed maybe Europeans would be healthier.
What impact does this have on
1) Britain's Industrial revolution (less money)?
2) US Society?