While rape in prison and health of prostitutes are issues to be handled, "ordinary" consensual heterosexual or homosexual activities remains the major route of transmissions, in addition to contamination of blood products. Also, safe sex practice would cover most routes of transmissions, apart from rape (which while deplorable, is and was not a major route of transmission in both absolute numbers and %), mother-child infection and contaminated blood products.
Actually the term should be safer sex not safe sex. The only truly safe sex is by yourself in the middle of the bed so you don't fall off and hurt yourself.