I'm not sure if this has been done before on the forum, but what-if Alexander the Great had went west into Italy, Illyria or Carthage instead of east into the Persian Empire? I challenge you to make a timeline based on this with the following stipulations
1. Philip II of Macedon must die on the exact same day as he did in OTL. However the means and consequences of his death are entirely up to you so long as they do not lead to conflict with Persia.
2. Macedon cannot come into conflict with Persia until 280 BC. To do this, you might have to change Philip's relations with Persia prior to his death.
3. Alexander cannot die by Persian hands, gold, etc.
4. Make it realistic (e.g. don't make Rome some sort of super power in the Mediterranean with a post-marian army, don't make Alexander discover America, etc.)
The timeline can go on as long as the creator wants of course, there is no time limit to it.