Any assumption that after the Battle of Rocroi it was realistic for Spain to do something seriously nasty to France is unrealistic. Anyway, Spain still was at war with France at the time of Fronde (all the way to 1659) and if it did not do anything of the kind it was not due to the lack of trying. Spain was also fighting in Italy and still battling the revolt in
Portugal and the French-backed
Catalan Revolt and any of those areas had been of a higher importance than invasion of France. Actually, they got into the French territory twice but without too much of success. Most of the fighting on the northern French-Spanish border was a standard inconclusive strategic dancing between Turenne on French side and Don Juan of Austria and Conde on Spanish until addition of the English contingent (with an explicit purpose to conquer Dunkirk) made it possible for Turenne to win a decisive victory in the
Battle of the Dunes. The rest was Spanish-French fighting in Italy and Catalonia with Spanish success in both cases.
They had been focusing on the Dutch. The main reason why they got involved in France was to prevent France to help the rebels (ditto for the whole issue with England). Parma marched into France only for a short time and his main purpose was to prevent the Catholic League from collapsing if Paris surrenders to Henry of Navarre. Isabella Clara was not even a serious side show being rejected by the Catholic party.
Actually, the whole enterprise failed miserably.
Of course, Henry VIII wanted to get them and Charles was very generous with the promises which would cost him nothing (one may only wonder why he did not promise Henry China as well). However, when Francis was Charles' prisoner and Henry came with his "you did promise!", he was advised to take a hike and not in the very polite terms.
From Henry?
How about "because they had to capture it first"?