Twining could be interesting - he took over the 20th from LeMay on 2nd August 1945, so was clearly thought to have potential. In fact, he became Chief of Staff of the Air Force in 1953, and Chairman of the Joint Chiefs of Staff in 1957.
Yet, in 1947, he was posted from command of Air Materiel Command to command the Alaskan Air Command - seems like an odd move. Sending him to SAC in place of LeMay seems very plausible to me, though I've no idea about his command style.
Incidentally, when talking of Doolittle as CINCSAC as less bloodthirsty than LeMay - remember who wrote these words: 'It is now clear that we are facing an implacable enemy whose avowed objective is world domination by whatever means and at whatever cost. There are no rules in such a game. Hitherto acceptable norms of human conduct do not apply. If the United States is to survive, long-standing American concepts of "fair play" msut be reconsidered.'
I doubt whether you'd see much difference in the broad strokes of policy between LeMay, Twining and Doolittle - all three were a product of the time. The difference would come in the nuances of how they implemented their policies; I doubt whether LeMay's attitude towards failure would be repeated, for instance.