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If any province(s) or diocese in the Roman Empire became the center of a new Roman empire (like the Byzantine Empire) ruled by a Roman usurper but "going native" or developing into its own tradition, which province would lead to the most interesting result, and why? If you're thinking of a pre-Christianity POD, also say what religion you think that new empire would adopt.
The secession from the empire would occur any time from 1 AD to 500 AD.
Closest OTL examples:
Syria (Palmyrene Empire)
Gaul (Gallic Empire)
Italia (Odoacer Rex Italiae)
Gaul (Syagrius)
Illyria (Julius Nepos)
An obvious option would be Africa and a new Roman empire ruled from Carthage. Another would be any King Arthur-inspired scenario in Britain, with a Romano-Briton usurper fighting the Saxons.