I have to agree with PHX 1138.
POD would probably have to be Kansas Governor Alf Landon winning the 1936 Presidential election (which was more possible than it's usually spun OTL) and not having nearly as many key advisors who were Soviet agents keeping us neutral until Hitler invaded Russia and greatly skewing the stories about China and Kai Shek. That'd make the USA credibly neutral into the war while also rebuilding the economy considerably between 1936-1940 instead of leaving it far below the 1920's and decaying. Avoiding the stupidity of FDR's "50,000 airplanes" for defense with a tiny ill-equipped Army or his yachtsman's experience after playing at Undersecretary of the Navy during WWI when the U.S. Navy just fought U-Boats for 2 years, the military would be in very different shape and configuration, albeit still quite small.
1942 Britain starved into submission with too much of it's merchant fleet lost to U-Boats without U.S. replacements and destroyer escorts to Iceland along with not making the sales of food, aviation gasoline (Battle of Britain with really menacing kites?), aircraft engines, ammunition, ship oil, metals, vacuum tubes, shoes, etc.. Signs a peace treaty with the Nazis to preserve it's empire and acknowledge it can't retake Europe, Churchill's government had already fallen. Manufacturing and military training shifts to India, Canada, Australia, Egypt to defend the empire that still includes 25% of the world's population.
Japan is in a quagmire in China with it too big and populous to conquer completely, assume it retains the Pacific Coast mostly and gives up on the interior by 1945-7. Chiang Kai Shek wipes out Mao's Communists as he nearly did several times and remains in control of some of the unoccupied China with the rest split up among the warlords and factions already in control there. It does the same with Vietnam and the Dutch East Indies, control the cities and ports along the coast and only address parts of the interiors where there are active mines, oil fields, etc. Singapore and the Kra Peninsula mean Japan's in effective control of most of the Pacific Coast of Asia and that's very far from both the British Navy and American Navy's supply sources. Britain signs a peace treaty ceding the lost territory to Japan in 1942 as well to retain India and Burma as well as end the threat to Australia and New Guinea, losing Singapore, Hong Kong, and Shanghai as well as investments and assets in China.
Stalin doesn't do nearly as well without the massive U.S. lend lease aid. He doesn't have the trucks, half-tracks, tanks, gasoline, food, tires, etc. to move his slaughtered armies back across Europe or outrun the German armored columns so the war there struggles on. John Mosier makes a surprising point that Stalin probably lost over 20 million soldiers and actually was running out manpower by 1943, and that Stalin's counterattack was only possible with the distraction of both the Allies Sicily-Italian invasions and clearly accumulating resources to invade France. Britain out of the war and without US aid and troops flowing in, Stalin is fighting alone and the battles are ever deeper in Soviet lands. Neither can quit but nor can they sustain the massive early battles as they're running low on men, equipment, fuel, food, and at the ends of their supply chains so sputtering down to a cease fire like the Koreas would in 1953 seems most likely. Russia's lost most of it's western area with most of it's population and industry as well as the Baku oil fields and port access to the Atlantic and Med, and probably a good chunk of mostly undefended Siberia and the port of Vladiovostok to the Japanese so by 1945 the USSR is far smaller, landlocked effectively between two major enemies and trying to build railroad and road connections to British India/Afghanistan/Nepal/Pakistan for trade routes.
The Reich's Lebensraum extermination of most of the population of Western Russia, Poland, Ukraine, Georgia, and much of France that the earlier slave labor camps were test models for (see Adam Tooze's "Wages of Destruction") proceeds and over 70 million civilians die, mostly worked to death through intentional starvation to build the new infrastructure and houses where they once lived. But Goebbel's control of Fortress Europe's media keeps the mass extermination a much debated, little known "story" not worth going to war over like the Jewish Holocaust, Armenian Genocide, Cambodia Killing Fields, Mao's Great Leap Forward, or Stalin's famines/kulak massacres/officer purges of perhaps 30 million in the 1930's. We don't want to know and determine there's nothing to be done as it's over probably as do the British.
The U.S. has had low taxes, productive use of people and capital for 10 years instead of a long Depression and horrifically expensive war in every measure. Baby Boom begins in the late 1930's but that's mostly postponed pregnancies from the Depression privations just as much of it was in OTL. The national television networks just starting in the late 1930's grow much faster without wartime shortages so electronics has advanced for consumer uses instead of direct military technologies like radar, sonar, code-breaking, etc. but Bell Labs, Raytheon, Hewlett Packard etc. still exist in the 1930's and without the distraction of defense work, entertainment technology, automotive electronics (AC Delco), avionics, sensors and controls, computing for accounting uses (IBM, Burroughs, Sperry, RCA, GE, etc.) continue to advance as they have since the 1890's Hollerith machines (which became IBM in 1912). American exports of cars, appliances, consumer electronics, farm equipment, hybrid seeds, gasoline, plastics, food, coal, steel, copper, movies, packaged foods, etc. grow far faster without the U-Boat threat and so much world trade and production disrupted.
Refugees from Europe and Asia provide a brain boost still to the US, Argentina, Brazil, Mexico, Phillipines, Australia, India, and Canada, both before and after the war. Israel isn't formed from British Palestine, too few Jews escape the Nazis and Stalin, and the Middle East is very different with it's primary customers and powers being the Germans, Italians, and Japanese. The U.S. remains the largest oil producer in the world while Russia, Saudi Arabia, Libya, Iran, Iraq stagnate with 1920's-30's drilling and refining technology (as Russia still was in the 1990's.) Argentina and South Africa are major trading partners of the Germans while the Belgian Congo, French North Africa, Algeria are now German colonies.
Those are my guesses, interesting question.