What PODs could result in the parties' views on tobacco being the opposite of OTL?

What PODs could result in concerns about things like Joe Camel, Big Tobacco's liability for smokers' healthcare, vaping being seen as crusades of the Religious Right and/or the Law and Order Right instead of as crusades of "Nanny State Liberals"? I know that C. Everett Koop was an Evangelical Republican.
 
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