What if no heamaphelia in the European Royal families?

There is a thread here asking what if Queen Victoria's heamaphelia had been worse. Let me aske the opposite question.

What if there had been no heamaphelia or other such conditions in any of the Royal Houses of Europe? I assume the heamaphelia came about or was as bad as it was because of in-breeding as royalty had to marry royalty. But what if there had been no heamephelia or other genetic diseases among any of the Royal Houses of Europe.

I'm sure it would have had a big impact on the Russian Imperial Family.
 
There is a thread here asking what if Queen Victoria's heamaphelia had been worse. Let me aske the opposite question.

What if there had been no heamaphelia or other such conditions in any of the Royal Houses of Europe? I assume the heamaphelia came about or was as bad as it was because of in-breeding as royalty had to marry royalty. But what if there had been no heamephelia or other genetic diseases among any of the Royal Houses of Europe.

I'm sure it would have had a big impact on the Russian Imperial Family.

Also on the Spanish one. The problem was in the big number of children and granchildren of Victoria because many of them inherit the gene responsible for haemophilia and transmit it to their children and thus the disease spread in the various European royal families
 
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