OTL the House of Representatives grew from 65 to 243 or so by 1840 - while the number of constituents per representative did not reach 50 000.
It was only with 1843 redistricting, that Representatives were deliberately shrunk and number of constituents jumped over 70 000.
So. If you compare the OTL size of Representatives with the size requied by Article the First - assuming the 1792 Connecticut ratification is not misfiled as it was per OTL, so it is applied on each redistricting since 1803. What are the respective Representative sizes, 1803-1853?
Bigger Representatives means bigger Electoral College - slightly less weight to smaller states (three-fifths?). What are the direct political effects of Article the First on the Presidential elections 1844-1860?