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Two Lucky Cities
When Sultan Murad II was succeeded by his son Mehmed II in early 1451, it was widely believed that the new young Sultan, who was by then 19 years old, would be an incapable ruler and could pose no great threat to Christian possessions in the Balkans and the Aegean. This belief was reinforced by Mehmed's friendly assurances to envoys who were sent to him at the beginning of his reign. During the spring and summer of 1452, Mehmed II, whose great grandfather Bayezid I had previously built a fortress on the Asian side of the Bosphorus called Anadolu Hisarı, now built a second fortress several miles north of Constantinople on the European side, directly across the strait from Anadolu Hisarı, which would increase Turkish influence on the straits. An especially relevant aspect of this fortress was its ability to prevent help from Genoese colonies on the Black Sea coast from reaching the city. This castle was called Rumeli Hisarı; Rumeli and Anadolu being the names of European and Asian portions of the Ottoman Empire, respectively. The new fortress is also known as Boğazkesen which has a dual meaning in Turkish: strait-blocker or throat-cutter, emphasizing its strategic position. The Greek name of the fortress, Laimokopia, also bears the same double-meaning.
Constantine Palaiologos XI signs a peace treaty with Murad II because he found out of the threat to Constantinople and agreed to be a vassal of the Ottoman Empire which he thinks would guarantee the survival of his empire.
Constantine Palaiologos marries the daughter of the Georgian King, George VIII of Georgia, the daughter of the Georgian King was renamed Sophia after their marriage in 1453 who have a daughter named Christina born in October 6 1454 however Constantine Palaiologos dies later on she would marry Ferdinand I, apparently Christina was sent to Naples to Alfonso of Aragon and betrothed to his illegitimate son they have a child called Manuel Trastamara born on October 8 1470 who marries a commoner and have child named Samantha Trastamara on October 8 1500
Isabella of Castille and Ferdinand of Castille marry as OTL and all of their male children die leaving Manuel of Avis as the the only male heir of Portugal, Castille and Aragon in 1520 he would marry Samantha Trastamara at the reign of her father Manuel Trastamara of Naples and Byzantium.
Thus Byzantium, Naples and Iberia are united however it is only France stopping them..

This is a sketch of this timeline I was actually creating a timeline where in both Selurong(present day city of manila) and Constantinople are not sacked by muslims.
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