At this time the world is looking at 60-70,000 nuclear weapons, some where between 50-25% of those going off is nearly an extinction level event. At the least we are looking at a regional extinction event. Now add Biological weapons to wreak havoc on much of what's left attacking people, crops, livestock and wildlife in parts of the world, like Africa and Latin America. Then add a world, where there are now no electricity, running water, food deliveries or hospitals. Between the climate changes, naturally occurring illness and disasters, injuries, accidents, and violence it could well mean the end of humanity as a species. Earth goes on without us.