From 1808 to 1813 the king of Spain, Charles IV, and his three sons - Ferdinand, Charles and Francis - were prisoners of Napoleon at the Chateau of Valençay. WI due to a contagious disease, food poisoning, a fire, whatever, all of them die there in 1810?
Spain was under Joseph Bonaparte. How would it affect the Peninsular War? Also, under Salic Law the Bourbon claimant would be the king of Two Sicilies (who now was ruling only Sicily). However, Charles' eldest daughter was Charlotte, queen of Portugal, who loved power so much that wanted to become Queen of La Plata "on behalf" of her exiled relatives. If she had any opportunity she would try to become Queen of Spain, but she was living in Rio de Janeiro with the Portuguese court.
Any ideas of what could happen from this?