Here's a rough idea of how a War of Nullification (1833 Civil war) could go.
South Carolina previously proclaimed that the Tariffs of 1828 and 1832 were unconstitutional, declared them null and void, and threatened to secede over the issue.
In March of 1832, the Supreme Court asked Federal Marshals to enforce the ruling in Worcester v Georgia. Jackson, despite disliking the ruling, obliged with the court's request - much to the chagrin of Georgia and to the frustration of other states and territories that sought Indian Removal: Mississippi, Alabama, and Florida.
Deep Southern States decide to take up the idea of Nullification and apply it to the Indian Removal Act, which dictates that only the President can negotiate Indian Removal. Nullification is the big political issue in the 1832 election.
Upon Jackson's reelection in 1832, four states and one territory secede: South Carolina, Georgia, Alabama, Mississippi, and Florida. And Jackson is the President staring them down.
Thoughts?