If you look at the view from port and starboard, that line running through the command pod is supposed to be a separation plane, with the destroyer sandwiched between the two parts and only its main weapons allowed to protrude in docked conformation, so an emergency blast-apart shouldn't be that hard.
Oh, I saw that line. My concern is that in the event when a speedy get away is necessary, that is a lot of mass that has to be ejected/pushed away. I would think that the inertia of that much mass might in some situations be an issue, but if you think that the defensive/other properties of the part outweigh that potential issue than that is what matters.
Re the crew and fighter complements, the intention was that the ship has quite a spidery hull and most of what interior space it does have is reserved for fuel and torpedo/missile storage for topping up the fleet craft when they dock: although I think the 300-odd I originally put is too small, I don't think it will be as high as you suggest for that reason (only a small part of the interior of the main hull would be inhabitable).
Aha, well, that makes sense. Perhaps a number between 500-1000 would be more representative of what is necessary.
Will post some more ships later and it should become clearer.
Looking forward to it.