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A little known fact on TR the great hunter was that during his 1903 tour of Yosemite the only animal he killed was a mouse he believe not yet know to science that he disected and preserved before sending to the Smithsonian.
What if he caught hantavirus from it, 6 weeks after the Yosemite visit on the way back to Washington DC after suffering what is thought to be a cold he dies in his sleep.
What effects will this have on the unfolding century.