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https://en.wikipedia.org/wiki/Mauser_MG_213
IOTL in 1942 the Germans started working a new cannon spec that that would fired 1000 rpm at 1000m/s muzzle velocity and ended up reinventing the revolver cannon concept, but actually creating a viable one that all the western allied nations adopted post-war when they each hired elements the Mauser development team. Apparently by 1945 the weapon was in an advanced state of development and post-war was redeveloped into different calibers for different Allied powers.
What if they had started early and got it into service in mid-1943? It fired at 2.5 times the cyclic rate of existing autocannons in aircraft, which made scoring hits very much easier, especially for enough hits to matter, while also increased the muzzle velocity by 33% over existing weapons. Is that enough to make rocket weapons pointless? Would it be enough to let single engine fighters actually deal with bombers from a safe distance with enough concentrated hitting power to do the job?

Edit:
say the Germans discover the Clark patent and decide to run with it.
http://www.cmchant.com/20th-century-revolver-cannon
There were many unsuccessful or impractical attempts to create a rapid-fire weapon from the early 18th century to the early 20th century before, in 1905, C. M. Clarke secured a US patent for the first fully automatic, gas-operated gun of the rotary-chamber type, but this design was ignored at the time as it appeared just as reciprocating-action automatic weapons such as the Maxim, Vickers and Browning water-cooled machine guns had been perfected and were becoming very popular in the world’s more advanced armies.
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