Super-preservative discovered earlier?

Bisin is a naturally occurring lantibiotic (an anti-bacterial peptide) discovered by University of Minnesota microbiologist Dan O'Sullivan. Unlike earlier lantibiotics discovered, such as nisin, bisin also kills Gram-negative bacteria, including E. coli, salmonella and listeria.
The food-preservative properties of bisin could lead to food products that resist spoilage for years. It was discovered by accident, something that could have happened earlier. (http://www.physorg.com/news/2011-08-microbiologist-super-preservative.html)


1. What is the earliest date it could have been discovered?

2. What effect would it have, if it was discovered earlier?
 
bacteria develop resistance in a couple of decades, and we're back to square one.

Bisin is produced by a bacteria that already colonized the human stomach. If other bacterias could easily develop resistance to it, wouldn't it have happened already?

I think this would be similar to a "what if earlier canning" question. It would change the processed food industry, creating a new industrial commodity and new jobs. This could lead to earlier urbanization and higher per cap GDP with all the knock on effects of yet more industrialization.
 
It is a peptide, a type of molecule (chains of amino acids but smaller than a protein) that is considerably more complex that f.ex penicillins. Synthesizing pure peptides in any larger quantities is difficult today and would be almost impossible a couple of decades ago.
 
Bisin is produced by a bacteria that already colonized the human stomach. If other bacterias could easily develop resistance to it, wouldn't it have happened already?
Penicillium notatum was producing penicillin for thousands (?millions?) of years, e.g.. It was only with the mass prescribing of antibiotics (to humans and animals) that antibiotic resistant bugs have become a severe problem.

If you have something that you add to foods in supermarkets so they don't have to be refrigerated, you're going develop resistance in no time flat.
 
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