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POD: Louis d'Anjou, King of Hungary, dies in the second year of his reign, in spring 1344 (classic horse riding accident). What happens then?
Two brothers of Louis are still alive, but Andrew is in Naples while Stephen is underaged. Andrew surely would claim the throne as oldest living son of Charles Robert, and Queen Mother would side with him. Andrew could improve his position in his marriage with Joanna, having his own Kingdom, more powerful than Naples. Also, Joanna would not be interested in his death now (if she really was involved in conspiracy that lead to his murder)-now thanks to marriage with Andrew she'd be not only Queen of Naples but Queen of Hungary too. Andrew would be outside reach of his OTL murderers, as he'd move to his native Hungary. Still, keeping power in both Naples and Hungary would not be easy-once Andrew and Joanna leave for Buda, remaining Angevins from Durazzo and Taranto lines would start making troubles. Usurpation of the throne by one of them (which one? Charles of Durazzo, married to Joanna's sister, has better claim) is question of time. So Hungary-Naples relations likely would not be any better than IOTL. Big winner is Andrew, who would avoid assassination, Joanna may lose Naples, but still would be better than IOTL as Queen of Hungary.