Originally, the seleucids ended up pretty miserable. Had they the chance to be an equal opponent of rome?
Can't say I think they could do it.
When the two empires met Rome was on the rise, their generals had learned their craft in a long and brutal war against Carthage, their armies had large numbers of veterans, their naval forces controlled the western med, and Rome had momentum on their side. In contrast the Seleucid empire was overstretched and their eastern enemies were waiting for a moment of weakness, but they were being lead by one of their best kings and were on a revival path.
Maybe if the second Macedonia war doesn't happens, and this is a big maybe has Rome never forgave the first war and they were waiting for an excuse for a fight, then Rome will be more focus in Illyria and Hispania, or if the Seleucid don't try to expand in Anatolia ensuring that the two empires don't step on each others areas of influence, then the Seleucids may be able to keep recovering and when Rome eventually turns east they may be in a better shape and can become a rival, which is possible because I doubt even the Romans were expecting such a big victory so fast.