Hmm interesting as wikipedia says this: Manfred's second wife was
Helena Angelina Doukaina,
[11] daughter of
Michael II Komnenos Doukas, ruler of the
despotate of Epirus, who made this marriage to ally with Manfred after being attacked by him at
Thessalonica. Helena and Manfred had four children:
Beatrix, Frederick, Henry and Azzolino. Helena and all her children were captured by Charles of Anjou after Manfred's death in 1266.
[13] Helena died in prison in
Nocera in 1271. The children were imprisoned in the
Castel dell'Ovo until they were moved to the
Castel Nuovo by
Charles II in 1299. Azzolino died first, followed by Henry in 1309. Beatrice had been released on the orders of the Aragonese commander
Roger of Lauria following a
battle off Naples in 1284. She went on to marry
Manfred IV, Marquis of Saluzzo.
[14] The eldest son, Frederick, escaped his prison and fled to Germany. He spent time in several European courts before dying in Egypt in 1312.